Brand Name(s):Neoral, Sandimmun, Capimune
Indication:Inflammatory Arthritis & Connective Tissue Disease for Adult Services, over 16, Transplantation, Immunosuppression, Non rheumatology indications
Ciclosporin is a critical-dose drug with a narrow therapeutic index
Care should be taken to stabilise the patient on a single brand of ciclosporin, and to ensure that the same brand of ciclosporin is always prescribed and dispensed to the patient
When switching of a patient stabilised to one brand of ciclosporin is unavoidable, the patient should be closely monitored for side effects, drug blood concentrations, and transplant function.
MHRA Drug Safety Update Volume 3 Issue 5 December 2009