Brand Name(s):Lojuxta

Indication:Lipid lowering-an adjunct to a low fat diet and other lipid lowering medicinal products with or without low density lipoprotein (LDL) apheresis in adult patients with homozygous familial hypercholesterolaemia



Review Date:May-26

Safety alert manufacurer warns . Screening for steatohepatitis should be performed before starting and then annually. The absence of pregnancy in women of child bearing potential should be confirmed before starting and effective contraception used whilst on treatment. April 2021

Extract from SPC Nov 2013
Genetic confirmation of HoFH should be obtained whenever possible. Other forms of primary hyperlipoproteinaemia and secondary causes of hypercholesterolaemia (e.g., nephrotic syndrome, hypothyroidism) must be excluded.