Topotecan

Red

Brand Name(s):Hycamtin, Potactasol

Indication:Recurrent and stage IVB cervical cancer

Rationale:1,2,3

Considered:Nov-09

Review Date:Jan-25

Comments:
Topotecan in combination with cisplatin is recommended as a treatment option for women with recurrent or stage IVB cervical cancer only if they have not previously received cisplatin.

Women who have previously received cisplatin and are currently being treated with topotecan in combination with cisplatin for recurrent and stage IVB cervical cancer should have the option to continue their therapy until they and their clinicians consider it appropriate to stop.

NICE TA 183 Topotecan for the treatment of recurrent and stage IVB cervical cancer October 2009