Rifaximin

Amber-G

Brand Name(s):Targaxan 550mg tab

Indication: Hepatic encephalopathy

Rationale:

Considered:Dec-14

Review Date:May-21

Comments:
Rifamixin is licensed for the reduction in recurrence of episodes of overt hepatic encephalopathy in patients aged 18 years or older. NICE guidance is based on 6-month trial data. A secondary care review will be undertaken at a maximum of six months following initiation. Continuation will be decided based on clinical efficacy.

The recommended dose is 550mg twice daily. The 200mg tablet (unlicensed) should not be prescribed.
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NICE TA337
Rifaximin (Targaxan) is recommended for preventing episodes of hepatic encephalopathy in people aged 18 years or older. Full information can be found at:http://www.nice.org.uk/guidance/ta337/resources/guidance-rifaximin-for-preventing-episodes-of-overt-hepatic-encephalopathy-pdf
Mar-2015