Quetiapine (XL formulation)

Amber

Brand Name(s):Seroquel XL

Indication:Add-on treatment of major depressive episodes in patients with Major Depressive Disorder (MDD)

Rationale:

Considered:Oct-10

Review Date:Jul-25

Comments:
Antipsychotic use may be associated with an increased risk of VTE. At present there are insufficient data available to determine any difference in risk between atypical and conventional antipsychotics, or between individual drugs. All possible risk factors for VTE should be identified before and during antipsychotic treatment and preventive measures undertaken

MHRA Drug safety update Volume 2 Issue 11 June 2009