Paliperidone

Amber-G

Brand Name(s):Invega

Indication:Antipsychotic – patients on the SMI register

Rationale:

Considered:Oct-07

Review Date:Oct-24

Comments:
NICE CG178
Psychosis and schizophrenia in adults: treatment and management
Full details at:https://www.nice.org.uk/guidance/cg178/resources/guidance-psychosis-and-schizophrenia-in-adults-treatment-and-management-pdf
Feb 2014

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MHRA Drug Safety Update November 2013
Risperidone and paliperidone: risk of intraoperative floppy iris syndrome in patients undergoing cataract surgery. More info at:http://www.mhra.gov.uk/Safetyinformation/DrugSafetyUpdate/CON336724
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Antipsychotic use may be associated with an increased risk of VTE. At present there are insufficient data available to determine any difference in risk between atypical and conventional antipsychotics, or between individual drugs. All possible risk factors for VTE should be identified before and during antipsychotic treatment and preventive measures undertaken
MHRA Drug safety update Volume 2 Issue 11 June 2009