Olanzapine

Amber

Brand Name(s):Zyprexa, Zyprexa Velotab

Indication:Antipsychotic – patients NOT on the SMI register

Rationale:1,2

Considered:Oct-19

Review Date:Oct-24

Comments:

Antipsychotic use may be associated with an increased risk of VTE. At present there are insufficient data available to determine any difference in risk between atypical and conventional antipsychotics, or between individual drugs. All possible risk factors for VTE should be identified before and during antipsychotic treatment and preventive measures undertaken

MHRA Drug safety update Volume 2 Issue 11 June 2009

All new initiations of antipsychotics in patients with dementia should be undertaken by specialist services and once established to be effective and at a stable dose transferred to Primary care.

Doncaster & Bassetlaw Area Prescribing Committee March 2009