Naltrexone

Red for new patients.
Amber-G for pre-existing

Brand Name(s):Nalorex

Indication:Managing Opioid dependance Alcohol disorders – maintenance of abstinence

Rationale:1,2

Considered:May-07

Review Date:May-22

Comments:
Naltrexone may be continued to be prescribed in Primary Care for pre-existing/historical patients, however no new patients should be initiated by, or transferred into, Primary Care. –
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Naltrexone can be offered in combination with an individual
psychological intervention (cognitive behavioural therapies, behavioural therapies or social network and environment-based therapies) focused specifically on alcohol misuse

NICE CG 115 Alochol Use Disorders
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Naltrexone is recommended as a treatment option in detoxified formerly opioid-dependent people who are highly motivated to remain in an abstinence programme

Naltrexone should only be administered under adequate supervision to people who have been fully informed of the potential adverse effects of treatment. It should be given as part of a programme of supportive care.

The effectiveness of naltrexone in preventing opioid misuse in people being treated should be reviewed regularly. Discontinuation of naltrexone treatment should be considered if there is evidence of such misuse.

NICE TA 115
Naltrexone for the management of opioid dependence January 2007
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