Nabilone

Red

Brand Name(s):

Indication:Control of nausea and vomiting, caused by chemotherapeutic agents used in the treatment of cancer, in patients who have failed to respond adequately to conventional antiemetic treatments.

Rationale:4

Considered:Dec-06

Review Date:Jan-22

Comments:
Drug abuse and dependence:
Nabilone is an abusable substance (it is a synthetic cannabinoid), capable of producing subjective side-effects, such as euphoria or “high”, at therapeutic doses. Prescriptions should be limited to the amount necessary for a single cycle of chemotherapy (i.e. a few days). The physical dependence capability of Nabilone is unknown. Patients who participated in clinical trials, up to 5 days duration, showed no withdrawal symptoms on cessation of dosing.

SPC Nabilone June 2008