Mifamurtide

Red

Brand Name(s):Mepact

Indication:Osteosarcoma

Rationale:1,2,3,8

Considered:Mar-10

Review Date:Mar-20

Comments:
Mifamurtide for the treatment of osteosarcoma
1 Guidance
1.1 Mifamurtide in combination with postoperative multi-agent chemotherapy is recommended
within its licensed indication as an option for the treatment of high-grade resectable nonmetastatic
osteosarcoma after macroscopically complete surgical resection in children,
adolescents and young adults and when mifamurtide is made available at a reduced cost to the
NHS under the patient access scheme.
NICE technology appraisal guidance 235 Issued: October 2011