Mesalazine

Amber-G

Brand Name(s):Asacol, Ipocol, Octasa, Pentasa,
Zintasa

Indication:Mild-moderate active ulcerative colitis and for maintenance of remission

Rationale:1,2,3,8

Considered:May-07

Review Date:Jul-23

Comments:
NICE CG 166
See document at:http://www.nice.org.uk/nicemedia/live/14189/64216/64216.pdf
Issued June 2013
…………………………
Monitoring for FBC & renal function is required:
a) Prior to starting Mesalazine then
b) 4-6 weeks after starting Mesalazine then
c) annually

Reference:
Local Gastroenterology advice is based upon British Society of Gastroenterologists Guideline for Management of Inflammatory Bowel Disease (2010).
SPC Asacol, Ipocol

March 2012 …………………………Revised SPC: Pentasa (mesalazine) preparations. Updated warning 2020 – cases of nephrolithiasis have been reported with the use of mesalazine, including stones with a 100% mesalazine content. It is recommended to ensure adequate fluid intake during treatment.