Dasatinib

Red

Brand Name(s):Zentiva

Indication:Philadelphia chromosome positive (Ph+) acute lymphoblastic leukaemia (ALL).

Rationale:1,2,3

Considered:Jan-20

Review Date:Jan-25

Comments:
Jan 20 – Dasatinib Zentiva is indicated for the treatment of paediatric patients with:newly diagnosed Ph+ ALL in combination with chemotherapy.

NICE TA 426
Dasatinib, nilotinib and imatinib for untreated chronic myeloid leukaemiaDasatinib, nilotinib and imatinib for untreated chronic myeloid leukaemia
NICE TA425
Dasatinib, nilotinib and high-dose imatinib for treating imatinib-resistant or intolerant chronic myeloid leukaemiaDasatinib, nilotinib and high-dose imatinib for treating imatinib-resistant or intolerant chronic myeloid leukaemia
Dec-16
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Drug Safety Update
Patients should be tested for hepatitis B virus before starting treatment with BCR-ABL tyrosine kinase inhibitors.
May2016