Apalutamide

Red

Brand Name(s):Erleada

Indication:Prostate Cancer (non-metastatic castration-resistant)
Metastatic Hormone Sensitive Prostate Cancer

Rationale:1,2,3

Considered:Feb-19

Review Date:Feb-25

Comments:
SPC has new recommendations to monitor for symptoms of IHD and management of CV risk factors.
Hypertension, hot flush, diarrhoea & weight loss have been added as common adverse effects
https://www.medicines.org.uk/emc/product/9832/smpc